I think we should never fall in love with our best friend. We could like break up with our boyfriend/ girlfriend and talk about your depression later to your best friend and how badly he/ she hurt u. But losing your best friend. I think its losing your other part of your soul or something. The break up will tore us apart. Thinking of small best friends who are opposite genders may look cute but if you took the bad path of it. This is how it would look like. So I think this is what I've got to say. Now it's your turn. Decide your own decision.